Season 4 boneless skinless chicken breasts with 1/4 teaspoon salt and 1/4 teaspoon pepper.
Gather three shallow bowls. In the first bowl, mix 1/4 cup flour and 1/2 teaspoon Cajun seasoning. In the second bowl, whisk 2 eggs. In the third bowl, combine 3/4 cup panko breadcrumbs and 1 cup Parmesan cheese.
Dredge each piece of chicken in the flour mixture, then into the eggs, and finally in the breadcrumb mixture.
Heat 1/4 cup oil in a skillet over medium-high heat. Cook the chicken until golden brown, about 5 minutes on each side. Remove from skillet.
Boil 10 ounces bowtie pasta according to package instructions. Drain and set aside.
In the same skillet, heat 1 tablespoon olive oil and sauté 1 red bell pepper, 1 yellow bell pepper, 1/4 cup onion, 1 cup mushrooms, and 2 teaspoons garlic until tender.
Remove the vegetables and return to the skillet. Melt 2 tablespoons butter, whisk in 1 tablespoon flour to create a roux.
Pour in 2 cups heavy cream and 3/4 cup low-sodium chicken broth. Stir in 1 cup Parmesan cheese and 1 tablespoon Cajun seasoning. Allow to thicken while stirring for 3-5 minutes.
Add the cooked pasta and sautéed vegetables to the sauce. Stir to combine.
Slice the chicken and layer on top of the pasta. Garnish with parsley and an optional dash of Cayenne pepper.